Normethadone
- R05DA06 (WHO)
- AU: S9 (Prohibited substance)
- BR: Class A1 (Narcotic drugs)[1]
- CA: Schedule I
- DE: Anlage III (Special prescription form required)
- US: Schedule I
- 6-dimethylamino-4,4-diphenyl-hexan-3-one
- 467-85-6 N
847-84-7 (HCl)
- 10090
- 9687 Y
- KR2L2A68XL
- D07384 Y
- ChEMBL346331 Y
- DTXSID6057748
- Interactive image
- O=C(C(c1ccccc1)(c2ccccc2)CCN(C)C)CC
- InChI=1S/C20H25NO/c1-4-19(22)20(15-16-21(2)3,17-11-7-5-8-12-17)18-13-9-6-10-14-18/h5-14H,4,15-16H2,1-3H3 Y
- Key:WCJFBSYALHQBSK-UHFFFAOYSA-N Y
Normethadone (INN, BAN; brand names Ticarda, Cophylac, Dacartil, Eucopon, Mepidon, Noramidone, Normedon, and others), also known as desmethylmethadone or phenyldimazone, is a synthetic opioid analgesic and antitussive agent.[citation needed] Normethadone is listed under the Single Convention on Narcotic Drugs 1961 and is a Schedule I Narcotic controlled substance in the United States, with a DEA ACSCN of 9635 and an annual manufacturing quota of 2 grams. It has an effective span of action for about 14 days, and is 12 to 20 times stronger than morphine. [2] The salts in use are the hydrobromide (free base conversion ratio 0.785), hydrochloride (0.890), methyliodide (0.675), oxalate (0.766), picrate (0.563), and the 2,6-ditertbutylnapthalindisulphonate (0.480).[3]
See also
References
- ^ Anvisa (2023-03-31). "RDC Nº 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial" [Collegiate Board Resolution No. 784 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control] (in Brazilian Portuguese). Diário Oficial da União (published 2023-04-04). Archived from the original on 2023-08-03. Retrieved 2023-08-16.
- ^ "Quotas - 2014". Diversion Control Division. U.S. Department of Justice, Drug Enforcement Administration. Archived from the original on 2016-03-04. Retrieved 2016-02-27.
- ^ Nordegren T (2002). "Normethadone". The A-Z encyclopedia of alcohol and drug abuse. Parkland, Fla.: Brown Walker Press. p. 470. ISBN 978-1-58112-404-0.
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- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
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