PAS结构域
| PAS折叠 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
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| 鑑定 | |||||||||||
| 標誌 | PAS | ||||||||||
| Pfam | PF00989（旧版） | ||||||||||
| InterPro（英语：InterPro） | IPR013767 | ||||||||||
| SMART（英语：Simple Modular Architecture Research Tool） | PAS | ||||||||||
| PROSITE（英语：PROSITE） | PDOC50112 | ||||||||||
| SCOP（英语：Structural Classification of Proteins） | 2phy / SUPFAM | ||||||||||
| CDD（英语：Conserved Domain Database） | cd00130 | ||||||||||
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PAS结构域（英語：PAS domain）也称为PAS折叠（英語：PAS fold）是一种在细菌、古菌和真核生物中都存在的蛋白质结构域[2]。其功能为检测小分子物质，如检测氧气的EPAS1等[3][4][5]。
参考文献
- ^ PDB 1y28; Dunham CM, Dioum EM, Tuckerman JR, Gonzalez G, Scott WG, Gilles-Gonzalez MA. A distal arginine in oxygen-sensing heme-PAS domains is essential to ligand binding, signal transduction, and structure. Biochemistry. July 2003, 42 (25): 7701–8 [2023-01-04]. PMID 12820879. doi:10.1021/bi0343370. （原始内容存档于2023-01-20）.
- ^ Henry, Jonathan T.; Crosson, Sean. Ligand-binding PAS domains in a genomic, cellular, and structural context. Annual Review of Microbiology. 1 January 2011, 65: 261–286. PMC 3298442
. PMID 21663441. doi:10.1146/annurev-micro-121809-151631. - ^ Liu, Yu C.; Machuca, Mayra A.; Beckham, Simone A.; Gunzburg, Menachem J.; Roujeinikova, Anna. Structural basis for amino-acid recognition and transmembrane signalling by tandem Per-Arnt-Sim (tandem PAS) chemoreceptor sensory domains. Acta Crystallographica Section D. 1 October 2015, 71 (10): 2127–2136. PMID 26457436. doi:10.1107/S139900471501384X.
- ^ Möglich, Andreas; Ayers, Rebecca A.; Moffat, Keith. Structure and signaling mechanism of Per-ARNT-Sim domains. Structure. 14 October 2009, 17 (10): 1282–1294. PMC 3092527 . PMID 19836329. doi:10.1016/j.str.2009.08.011.
- ^ Hennig, Sven; Strauss, Holger M.; Vanselow, Katja; Yildiz, Özkan; Schulze, Sabrina; Arens, Julia; Kramer, Achim; Wolf, Eva. Structural and Functional Analyses of PAS Domain Interactions of the Clock Proteins Drosophila PERIOD and Mouse PERIOD2. PLOS Biology. 28 April 2009, 7 (4): e1000094. PMC 2671562 . PMID 19402751. doi:10.1371/journal.pbio.1000094.
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