Cefuzonam

Cefuzonam
Klinički podaci

Drugs.com	Monografija
Identifikatori
CAS broj	82219-78-1^Y
ATC kod	none
PubChem	CID 6336505
ChemSpider	4891670^Y
UNII	860MT00T7T^Y
KEGG	D03432^Y
Hemijski podaci
Formula	C₁₆H₁₅N₇O₅S₄
Molarna masa	513,594
SMILES CO\N=C(/C(=N/[C@H]1[C@H]2SCC(=C(N2C1=O)C(=O)O)CSc3cnns3)/O)\C4=CSC(=N)N4
InChI InChI=1S/C16H15N7O5S4/c1-28-21-9(7-5-31-16(17)19-7)12(24)20-10-13(25)23-11(15(26)27)6(4-30-14(10)23)3-29-8-2-18-22-32-8/h2,5,10,14H,3-4H2,1H3,(H2,17,19)(H,20,24)(H,26,27)/b21-9-/t10-,14-/m1/s1^Y Key:CXHKZHZLDMQGFF-ZSDSSEDPSA-N^Y

Cefuzonam je organsko jedinjenje, koje sadrži 16 atoma ugljenika i ima molekulsku masu od 513,594 Da.

Osobine

Osobina	Vrednost
Broj akceptora vodonika	13
Broj donora vodonika	4
Broj rotacionih veza	8
Particioni koeficijent^[1] (ALogP)	0,4
Rastvorljivost^[2] (logS, log(mol/L))	-3,4
Polarna površina^[3] (PSA, Å²)	277,6

^ Ghose, A.K.; Viswanadhan V.N. & Wendoloski, J.J. (1998). „Prediction of Hydrophobic (Lipophilic) Properties of Small Organic Molecules Using Fragment Methods: An Analysis of AlogP and CLogP Methods”. J. Phys. Chem. A. 102: 3762—3772. doi:10.1021/jp980230o.
^ Tetko IV, Tanchuk VY, Kasheva TN, Villa AE (2001). „Estimation of Aqueous Solubility of Chemical Compounds Using E-State Indices”. Chem Inf. Comput. Sci. 41: 1488—1493. PMID 11749573. doi:10.1021/ci000392t.
^ Ertl P.; Rohde B.; Selzer P. (2000). „Fast calculation of molecular polar surface area as a sum of fragment based contributions and its application to the prediction of drug transport properties”. J. Med. Chem. 43: 3714—3717. PMID 11020286. doi:10.1021/jm000942e.

Hardman JG, Limbird LE, Gilman AG (2001). Goodman & Gilman's The Pharmacological Basis of Therapeutics (10. изд.). New York: McGraw-Hill. ISBN 0071354697. doi:10.1036/0071422803.
Thomas L. Lemke; David A. Williams, ур. (2007). Foye's Principles of Medicinal Chemistry (6. изд.). Baltimore: Lippincott Willams & Wilkins. ISBN 0781768799.