Disaharidaza
Disaharidaze su glikozidne hidrolaze, enzimi koji razlažu disaharide u jednostavnije šećere (monosaharide).[1] Genetički defekt jednog od tih enzima uzrokuje disaharidnu intoleranciju, kao što je laktozna intolerancija ili suharozna intolerancija.
Primeri disaharidaza
- Laktaza (razlaže laktozu U glukozu i galaktozu)
- Maltaza (razlaže maltozu u 2 glukoze)
- Saharaza (razlaže saharozu u glukozu i fruktozu)
- Trehalase (razlaže trehalozu u 2 glukoze)
Reference
- ↑ Charles Scriver, Beaudet, A.L., Valle, D., Sly, W.S., Vogelstein, B., Childs, B., Kinzler, K.W. (Accessed 2007). The Online Metabolic and Molecular Bases of Inherited Disease. New York: McGraw-Hill. - Summaries of 255 chapters, full text through many universities. There is also the OMMBID blog Arhivirano 2007-02-06 na Wayback Machine-u.
Literatura
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.
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Disaharidaze | |
|---|---|
Glukozidaze | Celulaza • Alfa-glukozidaza (Kisela, Neutralna AB, Neutralna C) • Beta-glukozidaza (citozolna) • Enzim umanjenja razgranatosti |
Drugi | Amilaza (Alfa-amilaza) • Hitinaza • Lizozim • Neuraminidaza (NEU1, NEU2, NEU3, NEU4, Bakterijska neuraminidaza, Viralna neuraminidaza) • Galaktozidaze (Alfa, Beta) • alfa-Manozidaza • Glukuronidaza • Hijaluronidaza • Pululanaza • Glukozilceramidaza (lizozomalna, nelizozomalna) • Galaktozilceramidaza • Alfa-N-acetilgalaktozaminidaza (NAGA) • Alfa-N-acetilglukozaminidaza • Fukozidaza • Heksozaminidaza (HEXA, HEXB) • Iduronidaza • Maltaza-glukoamilaza • Heparanaza (HPSE2) |
DNK glikozilaze: Oksoguanin glikozilaza
B enzm: 1.1/2/3/4/5/6/7/8/10/11/13/14/15-18, 2.1/2/3/4/5/6/7/8, 2.7.10, 2.7.11-12, 3.1/2/3/4/5/6/7, 3.1.3.48, 3.4.21/22/23/24, 4.1/2/3/4/5/6, 5.1/2/3/4/99, 6.1-3/4/5-6
