Tolciclate
Chemical compound
- D01AE19 (WHO)
- O-Tricyclo[6.2.1.02,7]undeca-2,4,6-trien-4-yl methyl(3-methylphenyl)carbamothioate
- 50838-36-3 Y
- 5506
- 5305 N
- T3TZ02X2AZ
- D01384 Y
- DTXSID0057758
- Interactive image
- Cc1cccc(c1)N(C)C(=S)Oc2ccc3c(c2)C4CCC3C4
InChI
- InChI=1S/C20H21NOS/c1-13-4-3-5-16(10-13)21(2)20(23)22-17-8-9-18-14-6-7-15(11-14)19(18)12-17/h3-5,8-10,12,14-15H,6-7,11H2,1-2H3 N
- Key:CANCCLAKQQHLNK-UHFFFAOYSA-N N
Tolciclate (INN)[1]: 9 is an antifungal medication.[2][3]
See also
- Tolnaftate
References
- ^ a b "International Nonproprietary Names for Pharmaceutical Substances (INN). Recommended International Nonproprietary names: List 15" (PDF). World Health Organization. 1975. Retrieved 12 November 2016.
- ^ Ryder NS, Frank I, Dupont MC (May 1986). "Ergosterol biosynthesis inhibition by the thiocarbamate antifungal agents tolnaftate and tolciclate". Antimicrobial Agents and Chemotherapy. 29 (5): 858–60. doi:10.1128/aac.29.5.858. PMC 284167. PMID 3524433.
- ^ Bianchi A, Monti G, de Carneri I (September 1977). "Tolciclate: further antimycotic studies". Antimicrobial Agents and Chemotherapy. 12 (3): 429–30. doi:10.1128/aac.12.3.429. PMC 429931. PMID 907333.
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Antifungals (D01 and J02)
membrane
Ergosterol inhibitors |
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β-glucan synthase inhibitors |
Pyrimidine analogues/ thymidylate synthase inhibitors |
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Mitotic inhibitors |
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Aminoacyl tRNA synthetase inhibitors |
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- bromochlorosalicylanilide
- chlorophetanol
- chlorphenesin
- ciclopirox
- crystal violet
- dimazole
- ethylparaben
- haloprogin‡
- polynoxylin
- potassium iodide#
- salicylic acid
- selenium disulfide#
- sodium thiosulfate#
- sulbentine
- taurolidine
- ticlatone
- tolciclate
- tolnaftate
- tribromometacresol
- undecylenic acid
- Whitfield's ointment#
- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
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