| STX1B |
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| Identifiers |
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| Aliases | STX1B, STX1B1, STX1B2, GEFSP9, syntaxin 1B |
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| External IDs | OMIM: 601485; MGI: 1930705; HomoloGene: 69375; GeneCards: STX1B; OMA:STX1B - orthologs |
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| Gene location (Human) |
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 | | Chr. | Chromosome 16 (human)[1] |
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| | Band | 16p11.2 | Start | 30,989,256 bp[1] |
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| End | 31,010,638 bp[1] |
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| Gene location (Mouse) |
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 | | Chr. | Chromosome 7 (mouse)[2] |
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| | Band | 7|7 F3 | Start | 127,403,072 bp[2] |
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| End | 127,423,721 bp[2] |
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| RNA expression pattern |
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| Bgee | | Human | Mouse (ortholog) |
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| Top expressed in | - right hemisphere of cerebellum
- right frontal lobe
- Brodmann area 9
- prefrontal cortex
- cingulate gyrus
- anterior cingulate cortex
- postcentral gyrus
- superior frontal gyrus
- nucleus accumbens
- hypothalamus
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| | Top expressed in | - superior frontal gyrus
- cerebellar cortex
- dentate gyrus of hippocampal formation granule cell
- pontine nuclei
- dorsal tegmental nucleus
- dorsomedial hypothalamic nucleus
- cerebellar vermis
- medial vestibular nucleus
- lobe of cerebellum
- subiculum
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| | More reference expression data |
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| BioGPS |  | | More reference expression data |
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| Gene ontology |
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| Molecular function | - SNAP receptor activity
- protein kinase binding
- signaling receptor binding
- SNARE binding
- protein domain specific binding
| | Cellular component | - integral component of membrane
- cytosol
- membrane
- synaptic vesicle
- plasma membrane
- spindle
- microtubule organizing center
- SNARE complex
- cytoskeleton
- nuclear lamina
- nucleus
- nucleoplasm
- centrosome
- cytoplasm
- presynaptic membrane
- presynapse
- presynaptic active zone membrane
- axon
- neuromuscular junction
- endomembrane system
| | Biological process | - synaptic vesicle docking
- spontaneous neurotransmitter secretion
- positive regulation of neurotransmitter secretion
- regulation of exocytosis
- vesicle docking
- positive regulation of excitatory postsynaptic potential
- regulation of gene expression
- protein transport
- intracellular protein transport
- neurotransmitter transport
- vesicle-mediated transport
- regulation of synaptic vesicle priming
- negative regulation of neuron projection development
- regulation of synaptic activity
- vesicle docking involved in exocytosis
- calcium ion-regulated exocytosis of neurotransmitter
- protein localization to membrane
- negative regulation of synaptic vesicle recycling
- positive regulation of spontaneous neurotransmitter secretion
- negative regulation of macropinocytosis
- synaptic vesicle fusion to presynaptic active zone membrane
- exocytic insertion of neurotransmitter receptor to postsynaptic membrane
- synaptic vesicle exocytosis
- exocytosis
- vesicle fusion
| | Sources:Amigo / QuickGO |
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| Orthologs |
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| Species | Human | Mouse |
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| Entrez | | |
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| Ensembl | | |
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| UniProt | | |
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| RefSeq (mRNA) | | |
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| RefSeq (protein) | | |
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| Location (UCSC) | Chr 16: 30.99 – 31.01 Mb | Chr 7: 127.4 – 127.42 Mb |
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| PubMed search | [3] | [4] |
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| Wikidata |
| View/Edit Human | View/Edit Mouse |
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1hvv: SELF-ASSOCIATION OF THE H3 REGION OF SYNTAXIN 1A: IMPLICATIONS FOR SNARE COMPLEX ASSEMBLY
1jth: Crystal structure and biophysical properties of a complex between the N-terminal region of SNAP25 and the SNARE region of syntaxin 1a
1kil: Three-dimensional structure of the complexin/SNARE complex
1n7s: High Resolution Structure of a Truncated Neuronal SNARE Complex
1urq: CRYSTAL STRUCTURE OF NEURONAL Q-SNARES IN COMPLEX WITH R-SNARE MOTIF OF TOMOSYN
