Lecirelin
Chemical compound
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Trade names | Dalmarelin, Ovucron, Reproreline |
Other names | H-Pyr-His-Trp-Ser-Tyr-D-Gly(tBu)-Leu-Arg-Pro-NHEt; XHWSYXLRP |
Routes of administration | Injection |
Drug class | GnRH agonist |
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ECHA InfoCard | 100.224.787 |
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Formula | C59H84N16O12 |
Molar mass | 1209.421 g·mol−1 |
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Lecirelin, sold under the brand names Dalmarelin, Ovucron, and Reproreline, is a short-acting gonadotropin-releasing hormone agonist (GnRH agonist) medication which is used in veterinary medicine in Europe and Israel.[1][2][3][4] It is a GnRH analogue and a synthetic peptide, specifically a nonapeptide.[1][2][3] The drug was introduced for veterinary use by 2000.[5] It is used in form of the acetate salt.[6]
See also
References
- ^ a b [1][dead link]
- ^ a b Farkas E, Ryadnov M (31 August 2013). Amino Acids, Peptide and Proteins. Royal Society of Chemistry. pp. 226–227. ISBN 978-1-84973-585-8.
- ^ a b Löscher W, Richter A, Potschka H (3 September 2014). Pharmakotherapie bei Haus- und Nutztieren: Begründet von W. Löscher, F.R. Ungemach und R. Kroker. Enke. pp. 435–. ISBN 978-3-8304-1251-9.
- ^ Speer B (21 December 2015). Current Therapy in Avian Medicine and Surgery - E-Book. Elsevier Health Sciences. pp. 448–. ISBN 978-0-323-24367-4.
- ^ Ahmad, G. (2000). Use of GNRH to improve the conception rate of Nili-Ravi buffaloes during low breeding season (Report).
- ^ Haberfeld H, ed. (2020). Austria-Codex (in German). Vienna: Österreichischer Apothekerverlag. Dalmarelin 25 Mikrogramm/ml Injektionslösung für Rinder und Kaninchen.
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GnRHTooltip Gonadotropin-releasing hormone and gonadotropins
(incl. analogues)
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Antagonists |
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(indirect)
- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
- See also
- GnRH and gonadotropin receptor modulators
- Androgens and antiandrogens
- Estrogens and antiestrogens
- Progestogens and antiprogestogens
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