ATG10

Protein-coding gene in the species Homo sapiens
ATG10
Identifiers
AliasesATG10, APG10, APG10L, pp12616, autophagy related 10
External IDsOMIM: 610800; MGI: 1914045; HomoloGene: 12036; GeneCards: ATG10; OMA:ATG10 - orthologs
Gene location (Human)
Chromosome 5 (human)
Chr.Chromosome 5 (human)[1]
Chromosome 5 (human)
Genomic location for ATG10
Genomic location for ATG10
Band5q14.1-q14.2Start81,972,023 bp[1]
End82,276,857 bp[1]
Gene location (Mouse)
Chromosome 13 (mouse)
Chr.Chromosome 13 (mouse)[2]
Chromosome 13 (mouse)
Genomic location for ATG10
Genomic location for ATG10
Band13|13 C3Start91,083,475 bp[2]
End91,372,087 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • testicle

  • gonad

  • islet of Langerhans

  • monocyte

  • ganglionic eminence

  • tibial arteries

  • skin of abdomen

  • gastrocnemius muscle

  • right coronary artery

  • stromal cell of endometrium
Top expressed in
  • interventricular septum

  • Epithelium of choroid plexus

  • epithelium of small intestine

  • myocardium of ventricle

  • intercostal muscle

  • right kidney

  • extraocular muscle

  • facial motor nucleus

  • Rostral migratory stream

  • lumbar spinal ganglion
More reference expression data
BioGPS
More reference expression data
Gene ontology
Molecular function
  • Atg12 transferase activity
  • transferase activity
Cellular component
  • cytoplasm
  • cytosol
  • intracellular anatomical structure
Biological process
  • autophagy
  • protein transport
  • protein modification by small protein conjugation
  • macroautophagy
  • positive regulation of protein modification process
  • ER overload response
  • protein lipidation
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

83734

66795

Ensembl

ENSG00000152348

ENSMUSG00000021619

UniProt

Q9H0Y0

Q8R1P4

RefSeq (mRNA)

NM_001131028
NM_031482

NM_025770

RefSeq (protein)

NP_001124500
NP_113670

NP_080046
NP_001391846
NP_001391847
NP_001391848
NP_001391849

NP_001391850
NP_001391851
NP_001391852
NP_001391854
NP_001391855
NP_001391856
NP_001391857

Location (UCSC)Chr 5: 81.97 – 82.28 MbChr 13: 91.08 – 91.37 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Autophagy-related protein 10 is a protein that in humans is encoded by the ATG10 gene.[5]


References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000152348 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000021619 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: ATG10 ATG10 autophagy related 10 homolog (S. cerevisiae)".


External links

Further reading

  • Feldman RD, Hunninghake GW, McArdle WL (1987). "Beta-adrenergic-receptor-mediated suppression of interleukin 2 receptors in human lymphocytes". J. Immunol. 139 (10): 3355–9. doi:10.4049/jimmunol.139.10.3355. PMID 2890687.
  • Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
  • Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
  • Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
  • Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
  • Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Mizushima N, Yoshimori T, Ohsumi Y (2003). "Mouse Apg10 as an Apg12-conjugating enzyme: analysis by the conjugation-mediated yeast two-hybrid method". FEBS Lett. 532 (3): 450–4. doi:10.1016/S0014-5793(02)03739-0. PMID 12482611. S2CID 37247321.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
  • Wan D, Gong Y, Qin W, et al. (2004). "Large-scale cDNA transfection screening for genes related to cancer development and progression". Proc. Natl. Acad. Sci. U.S.A. 101 (44): 15724–9. Bibcode:2004PNAS..10115724W. doi:10.1073/pnas.0404089101. PMC 524842. PMID 15498874.
  • Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.
  • Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.


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